Tottenham are close to completing the signings of Juventus players Dejan Kulusevski and Rodrigo Bentancur, while record signing Tanguy Ndombele has joined Lyon on loan.
Sweden winger Kulusevski, 21, is expected to join Antonio Conte's side on loan with an option to buy.
Uruguay midfielder Bentancur, 24, will be a permanent transfer.
France midfielder Ndombele returns to Lyon for the rest of the season - three years after leaving to join Spurs.
The 25-year-old joined Tottenham for a club record 60m euros (£53.8m).
Bentancur is a former Aston Villa target and is currently on World Cup duty with his country.
Meanwhile, Bryan Gil and Giovani lo Celso are also set to leave on loan.
Spain winger Gil, 20 - who only joined last July - is wanted by Valencia and Villarreal are targeting Argentina midfielder Lo Celso, 25.